The Guatemala Syphillis study http://www.nytimes.com/2010/10/02/health/research/02infect.html was unethical because physicians intentionally infected 700 prisoners, soldiers and mental patients without thier informed consent of the study. The study also hid information from Guatemala officials to keep the study from going domestic. When the study came to the light, codes like the Helsinki Declaration and the Nuremberg Code was in effect but not force by law. The apology that was given to the state of Guatemala is not enough they should have compensation paid to the inmates, mental patients and soldiers that was intentionally infected.
In the reading about the study of Tuskegee http://www.cdc.gov/tuskegee/timeline.htm it was unethical because the 400 men already infected with syphillis were led to believe that they were being treated for the disease. The study was suppose to last for six months but instead lasted for forty years, also the gentlemen were kept from getting cured when penicillin became the drug to cure syphilis in 1947, it was kept hidden from the subjects. The outcome of the study including the apology, ten million dollar settlement and the formation of The Tuskegee Health Benefit Program (THBP) which provides lifetime medical and burial services to all patients is a better acknowledgement of the situation compared to the Guatemala study.